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Cell biology

Chromosome territories

The natural habitat of eukaryotic genomes is the cell nucleus, where each chromosome is confined to a discrete region, referred to as a chromosome territory. This spatial organization is emerging as a crucial aspect of gene regulation and genome stability in health and disease.

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Figure 1: Spatial organization in the nucleus.
Figure 2: Arrangement of chromosome territories.

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Correspondence to Tom Misteli.

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Meaburn, K., Misteli, T. Chromosome territories. Nature 445, 379–381 (2007).

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