Accumulation of organized, self-polymerizing protein aggregates is a hallmark of Alzheimer's disease and infectious prion diseases. The similarities between these conditions may be even closer than that.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Selkoe, D. J. Nature 426, 900–904 (2003).
Harper, J. D. & Lansbury, P. T. Annu. Rev. Biochem. 66, 385–407 (1997).
Prusiner, S. Proc. Natl Acad. Sci. USA 95, 13363–13383 (1998).
Weissman, C. Nature Rev. Microbiol. 2, 861–871 (2004).
Meyer-Luehmann, M. et al. Science 313, 1781–1784 (2006).
Kane, M. D. et al. J. Neurosci. 20, 3606–3611 (2000).
Ridley, R. M. et al. J. Neural Transm. 113, 1243–1251 (2006).
Tanaka, M. et al. Nature 442, 585–589 (2006).
Petkova, A. T. et al. Biochemistry 45, 498–512 (2006).
Luhrs, T. et al. Proc. Natl Acad. Sci. USA 102, 17342–17347 (2005).
Aguzzi, A. & Heikenwalder, M. Nature Rev. Microbiol. 4, 765–775 (2006).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Riek, R. Infectious Alzheimer's disease?. Nature 444, 429–431 (2006). https://doi.org/10.1038/444429a
Published:
Issue Date:
DOI: https://doi.org/10.1038/444429a
This article is cited by
-
The activities of amyloids from a structural perspective
Nature (2016)
-
Nanomechanics of functional and pathological amyloid materials
Nature Nanotechnology (2011)
-
Insights into prion strains and neurotoxicity
Nature Reviews Molecular Cell Biology (2007)
