Mitochondria supply cells with energy, but in the process produce potentially damaging oxidants. It seems that a protein required to produce new mitochondria also protects against the resulting oxidative damage.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Reduced spermatozoa functionality during stress is the consequence of adrenergic-mediated disturbance of mitochondrial dynamics markers
Scientific Reports Open Access 08 October 2020
-
Decreased Mitochondrial Function, Biogenesis, and Degradation in Peripheral Blood Mononuclear Cells from Amyotrophic Lateral Sclerosis Patients as a Potential Tool for Biomarker Research
Molecular Neurobiology Open Access 25 August 2020
-
Oxidative stress, mitochondrial damage, and cores in muscle from calsequestrin-1 knockout mice
Skeletal Muscle Open Access 18 April 2015
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
St-Pierre, J. et al. Cell 127, 397–408 (2006).
Finck, B. N. & Kelly, D. P. J. Clin. Invest. 116, 615–622 (2006).
Puigserver, P. et al. Cell 92, 829–839 (1998).
Lin, J. et al. Cell 119, 121–135 (2004).
Leone, T. C. et al. PLoS Biol. 3, e101 (2005).
Hovatta, I. et al. Nature 438, 662–666 (2005).
Finkel, T. Curr. Opin. Cell Biol. 15, 247–254 (2003).
Nemoto, S., Takeda, K., Yu, Z. X., Ferrans, V. J. & Finkel, T. Mol. Cell Biol. 20, 7311–7318 (2000).
Werner, E. & Werb, Z. J. Cell Biol. 158, 357–368 (2002).
Lopez-Lluch, G. et al. Proc. Natl Acad. Sci. USA 103, 1768–1773 (2006).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Finkel, T. A clean energy programme. Nature 444, 151–152 (2006). https://doi.org/10.1038/444151a
Published:
Issue Date:
DOI: https://doi.org/10.1038/444151a
This article is cited by
-
Reduced spermatozoa functionality during stress is the consequence of adrenergic-mediated disturbance of mitochondrial dynamics markers
Scientific Reports (2020)
-
The interplay between oxidative stress and bioenergetic failure in neuropsychiatric illnesses: can we explain it and can we treat it?
Molecular Biology Reports (2020)
-
Decreased Mitochondrial Function, Biogenesis, and Degradation in Peripheral Blood Mononuclear Cells from Amyotrophic Lateral Sclerosis Patients as a Potential Tool for Biomarker Research
Molecular Neurobiology (2020)
-
Multi-regulatory network of ROS: the interconnection of ROS, PGC-1 alpha, and AMPK-SIRT1 during exercise
Journal of Physiology and Biochemistry (2017)
-
Peroxisome proliferator-activated receptor-γ–coactivator 1α (PGC-1α) gene expression in chronic kidney disease patients on hemodialysis: relation to hemodialysis-related cardiovascular morbidity and mortality
International Urology and Nephrology (2017)