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Ageing

Too fast by mistake

The intricate process of ageing involves numerous physiological pathways, together with genetic and environmental factors. Insight into this complex biology could come from studying a disorder that accelerates ageing.

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References

  1. 1

    Oeppen, J. & Vaupel, J. W. Science 296, 1029–1031 (2002).

    CAS  Article  Google Scholar 

  2. 2

    Kirkwood, T. B. L. Cell 120, 437–447 (2005).

    CAS  Article  Google Scholar 

  3. 3

    Finch, C. E. & Tanzi, R. E. Science 278, 407–411 (1997).

    ADS  CAS  Article  Google Scholar 

  4. 4

    Niedernhofer, L. J. et al. Nature 444, 1038–1043 (2006).

    ADS  CAS  Article  Google Scholar 

  5. 5

    Hasty, P., Campisi, J., Hoeijmakers, J., van Steeg, H. & Vijg, J. Science 299, 1355–1359 (2003).

    CAS  Article  Google Scholar 

  6. 6

    Hansen, M., Hsu, A. L., Dillin, A. & Kenyon, C. PLoS Genet. 1, 119–128 (2005).

    CAS  Article  Google Scholar 

  7. 7

    Lee, C. K., Klopp, R. G., Weindruch, R. & Prolla, T. A. Science 285, 1390–1393 (1999).

    CAS  Article  Google Scholar 

  8. 8

    Cao, S. X., Dhabhi, J. M., Mote, P. L. & Spindler, S. R. Proc. Natl Acad. Sci. USA 98, 10630–10635 (2001).

    ADS  CAS  Article  Google Scholar 

  9. 9

    Spindler, S. R. Mech. Ageing Dev. 126, 960–966 (2005).

    CAS  Article  Google Scholar 

  10. 10

    Kipling, D., Davis, T., Ostler, E. L. & Faragher, R. G. Science 305, 1426–1431 (2004).

    ADS  CAS  Article  Google Scholar 

Download references

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Kirkwood, T. Too fast by mistake. Nature 444, 1015–1017 (2006). https://doi.org/10.1038/4441015a

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