The finest scale of blood flow through the brain occurs in capillaries. Suspicions that capillary flow is regulated by cells that put the squeeze on these vessels are now borne out by detailed experiments.
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References
Roy, C. S. & Sherrington, C. S. J. Physiol. (Lond.) 11, 85–108 (1890).
Lauritzen, M. & Gold, L. J. Neurosci. 23, 3972–3980 (2003).
Peppiatt, C. M., Howarth, C., Mobbs, P. & Attwell, D. Nature 443, 700–704 (2006).
Chaigneau, E., Oheim, M., Audinat, E. & Charpak, S. Proc. Natl Acad. Sci. USA 100, 13081–13086 (2003).
Kleinfeld, D., Mitra, P. P., Helmchen, F. & Denk, W. Proc. Natl Acad. Sci. USA 95, 15741–15746 (1998).
Edvinsson, L. & Hamel, E. in Cerebral Blood Flow and Metabolism (eds Edvinsson, L. & Krause, D. N.) 43–70 (Lippincott Williams & Wilkins, Philadelphia, 2002).
Cauli, B. et al. J. Neurosci. 24, 8940–8949 (2004).
Mulligan, S. J. & MacVicar, B. A. Nature 431, 195–199 (2004).
Metea, M. R. & Newman, E. A. J. Neurosci. 26, 2862–2870 (2006).
Zonta, M. et al. Nature Neurosci. 6, 43–50 (2003).
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MacVicar, B., Salter, M. Controlled capillaries. Nature 443, 642–643 (2006). https://doi.org/10.1038/443642a
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DOI: https://doi.org/10.1038/443642a