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Physical chemistry

Seeds of phase change

Nature volume 443, page 641 (12 October 2006) | Download Citation


An effective but counter-intuitive trick to obtain highly ordered protein crystals is to 'seed' particles on disordered, porous surfaces. Computer simulations provide an explanation for the success of this strategy.

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Author information


  1. Daan Frenkel is at the FOM Institute for Atomic and Molecular Physics, Kruislaan 407, 1098SJ Amsterdam, The Netherlands.

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