Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Structural biology

Images from the surface of HIV

Human and monkey immunodeficiency viruses are studded with ‘spikes’ that enable them to infect cells. Structural studies reveal that these spikes are tripod-like assemblies that cluster on the virus surface.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Envelope spikes on the surface of HIV and SIV.


  1. Zhu, P. et al. Nature 441, 847–852 (2006).

    Article  ADS  CAS  Google Scholar 

  2. Zwick, M. B., Saphire, E. O. & Burton, D. R. Nature Med. 10, 133–134 (2004).

    Article  CAS  Google Scholar 

  3. Kwong, P. D. et al. Nature 393, 648–659 (1998).

    Article  ADS  CAS  Google Scholar 

  4. Chen, B. et al. Nature 433, 834–841 (2005).

    Article  ADS  CAS  Google Scholar 

  5. Kwong, P. D. et al. J. Virol. 74, 1961–1972 (2000).

    Article  CAS  Google Scholar 

  6. Zhu, P. et al. Proc. Natl Acad. Sci. USA 100, 15812–15817 (2003).

    Article  ADS  CAS  Google Scholar 

  7. Yang, X., Kurteva, S., Ren, X. & Sodroski, J. J. Virol. 80, 4388–4395 (2006).

    Article  CAS  Google Scholar 

  8. Kuznetsov, Y. G., Victoria, J. G., Robinson, W. E. Jr & McPherson, A. J. Virol. 77, 11896–11909 (2003).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations


Rights and permissions

Reprints and permissions

About this article

Cite this article

Burton, D. Images from the surface of HIV. Nature 441, 817–818 (2006).

Download citation

  • Published:

  • Issue Date:

  • DOI:


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing