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Neurobiology

Extending influence

Rather than merely firing in a digital on–off fashion, vertebrate neurons may have an analogue aspect to their signalling too — a finding that will not surprise many who have worked on invertebrate neurons.

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Figure 1: Analogue signalling.

References

  1. Zucker, R. S. & Regehr, W. G. Annu. Rev. Physiol. 64, 355–405 (2002).

    Article  CAS  Google Scholar 

  2. Alle, H. & Geiger, J. R. Science 311, 1290–1293 (2006).

    Article  ADS  CAS  Google Scholar 

  3. Shu, Y., Hasenstaub, A., Duque, A., Yu, Y. & McCormick, D. A. Nature 441, 761–765 (2006).

    Article  ADS  CAS  Google Scholar 

  4. Kandel, E. R., Schwartz, J. H. & Jessell, T. M. Principles of Neural Science (McGraw–Hill, New York, 2000).

    Google Scholar 

  5. Meyrand, P. et al. J. Neurosci. 12, 2803–2812 (1992).

    Article  CAS  Google Scholar 

  6. Sabatini, B. L. & Regehr, W. G. J. Neurosci. 17, 3425–3435 (1997).

    Article  CAS  Google Scholar 

  7. Ma, M. & Koester, J. J. Neurosci. 16, 4089–4101 (1996).

    Article  CAS  Google Scholar 

  8. Selverston, A. I. et al. Prog. Neurobiol. 7, 215–290 (1976).

    Article  CAS  Google Scholar 

  9. Ayali, A. et al. J. Neurophysiol. 79, 2063–2069 (1998).

    Article  CAS  Google Scholar 

  10. Angstadt, J. D. & Calabrese, R. L. J. Neurosci. 11, 746–759 (1991).

    Article  CAS  Google Scholar 

  11. Graubard, K. et al. Proc. Natl Acad. Sci. USA 77, 3733–3735 (1980).

    Article  ADS  CAS  Google Scholar 

  12. Graubard, K. J. Neurophysiol. 41, 1014–1025 (1978).

    Article  CAS  Google Scholar 

  13. Manor, Y. et al. J. Neurosci. 17, 5610–5621 (1997).

    Article  CAS  Google Scholar 

  14. DiCaprio, R. A. J. Comp. Neurol. 185, 83–106 (1989).

    Article  Google Scholar 

  15. Burrows, M. & Siegler, M. V. J. Physiol. (Lond.) 285, 231–255 (1978).

    Article  CAS  Google Scholar 

  16. Werblin, F. S. & Dowling, J. E. J. Neurophysiol. 32, 339–355 (1969).

    Article  CAS  Google Scholar 

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Marder, E. Extending influence. Nature 441, 702–703 (2006). https://doi.org/10.1038/441702a

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