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Microbiology

Antibiotic stops ‘ping-pong’ match

As bacteria become resistant to existing drugs, there is a need for antibiotics with new modes of action. Such a compound has been found, and it works by binding to an intermediate in the catalytic cycle of its target.

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Figure 1: The catalytic cycle of FabF for fatty-acid biosynthesis in bacteria.

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Brown, E. Antibiotic stops ‘ping-pong’ match. Nature 441, 293–294 (2006). https://doi.org/10.1038/441293a

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