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Methane and microbes

Microorganisms can carry out a wonderful range of chemical transformations. The anaerobic oxidation of methane seemed not to be among them. But it is — both with sulphate, and now it turns out, with nitrate.

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Figure 1: The anaerobic oxidation of methane (CH4).
Figure 2: Nitrate-dependent anaerobic oxidation of methane1 and related processes.


  1. Raghoebarsing, A. A. et al. Nature 440, 918–921 (2006).

    Article  ADS  CAS  Google Scholar 

  2. Grossman, E. L., Cifuentes, L. A. & Cozzarelli, I. M. Environ. Sci. Technol. 36, 2436–2442 (2002).

    Article  ADS  CAS  Google Scholar 

  3. Valentine, D. L. & Reeburgh, W. S. Environ. Microbiol. 2, 477–484 (2000).

    Article  CAS  Google Scholar 

  4. Boetius, A. et al. Nature 407, 623–626 (2000).

    Article  ADS  CAS  Google Scholar 

  5. Thauer, R. K., Jungermann, K. & Decker, K. Bacteriol. Rev. 41, 100–180 (1977).

    CAS  PubMed  PubMed Central  Google Scholar 

  6. Krüger, M. et al. Nature 426, 878–881 (2003).

    Article  ADS  Google Scholar 

  7. Hallam, S. J. et al. Appl. Environ. Microbiol. 69, 5483–5491 (2003).

    Article  CAS  Google Scholar 

  8. Shima, S. & Thauer, R. K. Curr. Opin. Microbiol. 8, 643–648 (2005).

    Article  CAS  Google Scholar 

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Thauer, R., Shima, S. Methane and microbes. Nature 440, 878–879 (2006).

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