Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Molecular biology

Prime-time progress

DNA is duplicated within a complex macromolecular machine. Insights into how replication begins and how this is coordinated with progression of DNA synthesis come from a diverse range of sources.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: DNA replication.
Figure 2: Co-opting other enzymes for priming.

References

  1. Heller, R. C. & Marians, K. J. Nature 439, 557–562 (2006).

    Article  ADS  CAS  Google Scholar 

  2. Lee, J. -B. et al. Nature 439, 621–624 (2006).

    Article  ADS  CAS  Google Scholar 

  3. Zenkin, N., Naryshkina, T., Kuznedelov, K. & Severinov, K. Nature 439, 617–620 (2006).

    Article  ADS  CAS  Google Scholar 

  4. Kornberg, A. & Baker, T. A. DNA Replication 2nd edn (Freeman, New York, 1992).

    Google Scholar 

  5. Frick, D. N. & Richardson, C. C. Annu. Rev. Biochem. 70, 39–80 (2001).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bell, S. Prime-time progress. Nature 439, 542–543 (2006). https://doi.org/10.1038/439542a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/439542a

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing