Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Development

Twists of fate in the brain

How does the complex array of cell types and functions in the mammalian brain develop? Tracking cells by gene expression shows how their fates derive from organization within the simple embryonic neural tube.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Fate in the rhombic lip.

References

  1. Zinyk, D. L., Mercer, E. H., Harris, E., Anderson, D. J. & Joyner, A. L. Curr. Biol. 8, 665–668 (1998).

    Article  CAS  Google Scholar 

  2. Branda, C. S. & Dymecki, S. M. Dev. Cell 6, 7–28 (2004).

    Article  CAS  Google Scholar 

  3. Machold, R. & Fishell, G. Neuron 48, 17–24 (2005).

    Article  CAS  Google Scholar 

  4. Wang, V. Y. et al. Neuron 48, 31–43 (2005).

    Article  CAS  Google Scholar 

  5. Landsberg, R. I. et al. Neuron 48, 933–947 (2005).

    Article  CAS  Google Scholar 

  6. Jessell, T. M. Nature Rev. Genet. 1, 20–29 (2000).

    Article  CAS  Google Scholar 

  7. Lin, J. C. & Cepko, C. L. J. Neurosci. 21, 159–168 (2001).

    Article  CAS  Google Scholar 

  8. Currle, D. S., Cheng, X., Hsu, C. M. & Monuki, E. S. Development 132, 3549–3559 (2005).

    Article  CAS  Google Scholar 

  9. Hoshino, M. et al. Neuron 47, 201–213 (2005).

    Article  CAS  Google Scholar 

  10. Sgaier, S. K. et al. Neuron 45, 27–40 (2005).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pearse, R., Tabin, C. Twists of fate in the brain. Nature 439, 404–405 (2006). https://doi.org/10.1038/439404a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/439404a

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing