Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Developmental biology

Tiny brakes for a growing heart

The discovery of microRNAs has revolutionized many areas of biology. The latest news is that these RNAs seem to regulate the crucial balance between growth and specialization of cardiac cells.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Heart development and miR-1.

References

  1. Ambros, V. Nature 431, 350–355 (2004).

    Article  ADS  CAS  Google Scholar 

  2. Bartel, D. P. Cell 116, 281–297 (2004).

    Article  CAS  Google Scholar 

  3. Lagos-Quintana, M. et al. Curr. Biol. 12, 735–739 (2002).

    Article  CAS  Google Scholar 

  4. Lim, L. P. et al. Nature 433, 769–773 (2005).

    Article  ADS  CAS  Google Scholar 

  5. Mansfield, J. H. et al. Nature Genet. 36, 1079–1083 (2004).

    Article  CAS  Google Scholar 

  6. Wienholds, E. et al. Science advance online publication, 26 May 2005 (doi:10.1126/science.1114519).

  7. Zhao, Y., Samal, E. & Srivastava, D. Nature 436, 214–220 (2005).

    Article  ADS  CAS  Google Scholar 

  8. Giraldez, A. J. et al. Science 308, 833–888 (2005).

    Article  ADS  CAS  Google Scholar 

  9. Srivastava, D. & Olson, E. N. Nature 407, 221–226 (2000).

    Article  CAS  Google Scholar 

  10. Bruneau, B. G. Clin. Genet. 63, 252–261 (2003).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bruneau, B. Tiny brakes for a growing heart. Nature 436, 181–182 (2005). https://doi.org/10.1038/436181a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/436181a

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing