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Cancer biology

The weakest link?

Cellular lineages are defined by master regulatory proteins that dictate their fate and ensure their survival. The dependence on such factors of tumours that are resistant to treatment may prove to be their Achilles' heel.

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Figure 1: A master regulator in melanoma.

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Merlino, G. The weakest link?. Nature 436, 33–35 (2005). https://doi.org/10.1038/436033a

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