Embryonic cells learn their fate early in development. Discovery of a factor that controls the development of one embryonic tissue, the ectoderm, highlights a mechanism that might also influence the growth of cancer cells.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
References
Wolpert, L. Dev. Suppl. 7–13 (1992).
Dupont, S. et al. Cell 121, 87–99 (2005).
Gerhart, J. Int. J. Dev. Biol. 43, 605–613 (1999).
Zhang, J. et al. Cell 94, 515–524 (1998).
Agius, E. et al. Development 127, 1173–1183 (2000).
Fainsod, A., Steinbeisser, H. & De Robertis, E. M. EMBO J. 13, 5015–5025 (1994).
Collignon, J., Varlet, I. & Robertson, E. J. Nature 381, 155–158 (1996).
Siegel, P. M. & Massagué, J. Nature Rev. Cancer 3, 807–821 (2003).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Sasai, Y. A blank canvas no more. Nature 435, 433–434 (2005). https://doi.org/10.1038/435433a
Published:
Issue Date:
DOI: https://doi.org/10.1038/435433a
This article is cited by
-
Development and differentiation of neural rosettes derived from human embryonic stem cells
Stem Cell Reviews (2006)