Kinesin is a protein motor that ferries membrane-bound packages around cells — but only in one direction. Forcing it into reverse provides clues to its inner workings and to how molecular machines might be engineered.
This is a preview of subscription content, access via your institution
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Prices vary by article type
Prices may be subject to local taxes which are calculated during checkout
Carter, N. J. & Cross, R. A. Nature 435, 308–312 (2005).
Svoboda, K., Schmidt, C. F., Schnapp, B. J. & Block, S. M. Nature 365, 721–727 (1993).
Knight, A. E. & Molloy, J. E. Nature Cell Biol. 1, E87–E89 (1999).
Yildiz, A., Tomishige, M., Vale, R. D. & Selvin, P. R. Science 303, 676–678 (2004).
Noji, H., Yasuda, R., Yoshida, M. & Kinosita, K. Nature 386, 299–302 (1997).
Abrahams, J. P., Leslie, A. G., Lutter, R. & Walker, J. E. Nature 370, 621–628 (1994).
Henningsen, U. & Schliwa, M. Nature 389, 93–96 (1997).
Tsiavaliaris, G., Fujita-Becker, S. & Manstein, D. J. Nature 427, 558–561 (2004).
About this article
Cite this article
Molloy, J., Schmitz, S. Kinesin steps back. Nature 435, 285–287 (2005). https://doi.org/10.1038/435285a