Kinesin is a protein motor that ferries membrane-bound packages around cells — but only in one direction. Forcing it into reverse provides clues to its inner workings and to how molecular machines might be engineered.
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Molloy, J., Schmitz, S. Kinesin steps back. Nature 435, 285–287 (2005). https://doi.org/10.1038/435285a
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DOI: https://doi.org/10.1038/435285a