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Gene regulation

Expression and silencing coupled

The RNA interference pathway can inhibit the expression of specific genes. It now seems that an essential component of the silencing process is the gene-expression machinery itself.

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Figure 1: Transcription-coupled RNA interference.

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Buratowski, S., Moazed, D. Expression and silencing coupled. Nature 435, 1174–1175 (2005). https://doi.org/10.1038/4351174b

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