TRP channels are best known for their role in sensory systems: detecting heat and cold, taste, pain and so on. Unexpectedly, they have also been shown to help the growing axons of nerve cells find their way.
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Wang, G. X. & Poo, M. Nature 434, 898–904 (2005).
Li, Y. et al. Nature 434, 894–898 (2005).
Hong, K., Nishiyama, M., Henley, J., Tessier-Lavigne, M. & Poo, M. Nature 403, 93–98 (2000).
Montell, C., Birnbaumer, L. & Flockerzi, V. Cell 108, 595–598 (2002).
Greka, A., Navarro, B., Oancea, E., Duggan, A. & Clapham, D. E. Nature Neurosci. 6, 837–845 (2003).
Jin, M. et al. J. Neurosci. 25, 2338–2347 (2005).
Wen, Z. X., Guirland, C., Ming, G. L. & Zheng, J. Q. Neuron 43, 835–846 (2004).
Robles, E., Huttenlocher, A. & Gomez, T. M. Neuron 38, 597–609 (2003).
Henley, J. R., Huang, K. H., Wang, D. & Poo, M. M. Neuron 44, 909–916 (2004).
Nishiyama, M. et al. Nature 423, 990–995 (2003).
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Gomez, T. Channels for pathfinding. Nature 434, 835–837 (2005). https://doi.org/10.1038/434835a
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