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Biochemistry

A pore way to die

Like Jekyll to Hyde, mitochondria can change from acting as the cell's powerhouses to become merciless killers. Mice lacking this mechanism develop normally, and their hearts are resistant to pathological damage.

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Figure 1: A killing machine.

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Halestrap, A. A pore way to die. Nature 434, 578–579 (2005). https://doi.org/10.1038/434578a

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