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Spectroscopy at a stretch

Two-dimensional spectroscopy can now be done using visible light. This allows the electronic couplings between energy levels to be measured directly and sheds new light on how molecules function in photosynthesis.

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  1. Ernst, R. R. Principles of Nuclear Magnetic Resonances in One and Two Dimensions (Oxford Univ. Press, 1987).

    Google Scholar 

  2. Brixner, T. et al. Nature 434, 625–628 (2005).

    Article  ADS  CAS  Google Scholar 

  3. Gorcester, J. & Freed, J. H. J. Chem. Phys. 88, 4678–4693 (1988).

    Article  ADS  CAS  Google Scholar 

  4. Asplund, M. C., Zanni, M. T. & Hochstrasser, R. M. Proc. Natl Acad. Sci. USA 97, 8219–8224 (2000).

    Article  ADS  CAS  Google Scholar 

  5. Mukamel, S. Annu. Rev. Phys. Chem. 51, 691–729 (2000).

    Article  ADS  CAS  Google Scholar 

  6. Hamm, P. & Hochstrasser, R. M. Pract. Spectrosc. 26, 273–347 (2001).

    CAS  Google Scholar 

  7. Zanni, M. T. & Hochstrasser, R. M. Curr. Opin. Struct. Biol. 11, 516–522 (2001).

    Article  CAS  Google Scholar 

  8. Ge, N. -H. et al. J. Phys. Chem. A 106, 962–972 (2002).

    Article  CAS  Google Scholar 

  9. Chung Hoi, S., Khalil, M., Smith, A. W., Ganim, Z. & Tokmakoff, A. Proc. Natl Acad. Sci. USA 102, 612–617 (2005).

    Article  ADS  Google Scholar 

  10. Kim, Y. S. & Hochstrasser, R. M. J. Phys. Chem. B doi:10.1021/jp0449511 (2005).

  11. Asbury, J. B. et al. J. Chem. Phys. 121, 12431–12446 (2004).

    Article  ADS  CAS  Google Scholar 

  12. Mok, K. H. et al. J. Am. Chem. Soc. 125, 12484–12492 (2003).

    Article  CAS  Google Scholar 

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Hochstrasser, R. Spectroscopy at a stretch. Nature 434, 570–571 (2005).

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