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Structural biology

DNA search and rescue

Nature volume 434, pages 569–570 (2005)Cite this article

How do DNA-repair enzymes find aberrant nucleotides among the myriad of normal ones? One enzyme has been caught in the act of checking for damage, providing clues to its quality-control process.

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Figure 1: Damage detection — how hOGG1 searches for damaged guanine residues (oxoG, or oG), based on the findings of Banerjee and colleagues1.

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  1. the Department of Chemistry, University of Utah, 315 South 1400 East, Salt Lake City, 84112, Utah, USA

    Sheila S. David

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  1. Sheila S. David
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David, S. DNA search and rescue. Nature 434, 569–570 (2005). https://doi.org/10.1038/434569a

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