Are syphilis epidemics caused by external factors such as human sexual behaviour, or are factors intrinsic to the pathogen more important? Comparing the dynamics of syphilis and gonorrhoea provides some clues.
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Grenfell, B., Bjørnstad, O. Epidemic cycling and immunity. Nature 433, 366–367 (2005). https://doi.org/10.1038/433366a
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DOI: https://doi.org/10.1038/433366a