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Knockout malaria vaccine?

An effective vaccine against malaria remains elusive. But the finding that a genetically manipulated malaria parasite can protect its host lends fresh appeal to the idea of vaccines involving live attenuated parasites.

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Figure 1: The Plasmodium life cycle and antimalarial vaccination strategies.


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Ménard, R. Knockout malaria vaccine?. Nature 433, 113–114 (2005).

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