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Human immunodeficiency virus

Nuclear RNA export unwound

The ways in which HIV can subvert cellular processes for its own ends seem boundless. The latest discovery — a cellular enzyme that helps to export HIV RNA from the nucleus — reveals a possible drug target.

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Figure 1: Escape from the nucleus: how cellular and HIV-1 messenger RNAs are exported.

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Cullen, B. Nuclear RNA export unwound. Nature 433, 26–27 (2005). https://doi.org/10.1038/433026a

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