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Developmental biology

No red cell is an island

Red blood cells develop in the bone marrow in ‘islands’ nurtured by a central white blood cell. Work in mice shows that the retinoblastoma protein is crucial for these white cells to mature and form islands.

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Figure 1: Erythroblast islands.

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Palis, J. No red cell is an island. Nature 432, 964–965 (2004). https://doi.org/10.1038/432964a

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