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Regenerative medicine

Prometheus unbound

The discovery of a protein that stimulates cell migration and survival in damaged mouse hearts suggests a potential new approach to the treatment of heart attacks.

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Figure 1: Cardiac repair in legend, counter-legend, and reality.

References

  1. Bock-Marquette, I. et al. Nature 432, 466–472 (2004).

    ADS  CAS  Article  Google Scholar 

  2. Rosenthal, N. N. Engl. J. Med. 349, 267–274 (2003).

    Article  Google Scholar 

  3. Borowiak, M. et al. Proc. Natl Acad. Sci. USA 101, 10608–10613 (2004).

    ADS  CAS  Article  Google Scholar 

  4. Mathur, A. & Martin, J. F. Lancet 364, 183–192 (2004).

    CAS  Article  Google Scholar 

  5. Olson, E. N. & Schneider, M. D. Genes Dev. 17, 1937–1956 (2003).

    CAS  Article  Google Scholar 

  6. Leobon, B. et al. Proc. Natl Acad. Sci. USA 100, 7808–7811 (2003).

    ADS  CAS  Article  Google Scholar 

  7. Balsam, L. B. et al. Nature 428, 668–673 (2004).

    ADS  CAS  Article  Google Scholar 

  8. Murry, C. E. et al. Nature 428, 664–668 (2004).

    ADS  CAS  Article  Google Scholar 

  9. Nygren, J. M. et al. Nature Med. 10, 494–501 (2004).

    CAS  Article  Google Scholar 

  10. Hertzog, M. et al. Cell 117, 611–623 (2004).

    CAS  Article  Google Scholar 

  11. Philp, D., Goldstein, A. L. & Kleinman, H. K. Mech. Ageing Dev. 125, 113–115 (2004).

    CAS  Article  Google Scholar 

  12. Brazil, D. P., Park, J. & Hemmings, B. A. Cell 111, 293–303 (2002).

    CAS  Article  Google Scholar 

  13. Fujio, Y., Nguyen, T., Wencker, D., Kitsis, R. N. & Walsh, K. Circulation 101, 660–667 (2000).

    CAS  Article  Google Scholar 

  14. Oh, H. et al. Proc. Natl Acad. Sci. USA 100, 12313–12318 (2003).

    ADS  CAS  Article  Google Scholar 

  15. Musaro, A. et al. Proc. Natl Acad. Sci. USA 101, 1206–1210 (2004).

    ADS  CAS  Article  Google Scholar 

  16. Mangi, A. A. et al. Nature Med. 9, 1195–1201 (2003).

    CAS  Article  Google Scholar 

Download references

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Schneider, M. Prometheus unbound. Nature 432, 451–453 (2004). https://doi.org/10.1038/432451a

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