Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Circadian rythms

Sunrise and sunset in fly brains

Nature volume 431, pages 751–752 (2004)Cite this article

Fruitflies can time their morning and evening activities to the day–night cycle. The basic circadian oscillatory mechanism is intracellular, but networks of cells, now being identified, are what make a working clock.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Clock-gene-expressing neurons and their outputs in the fruitfly brain.

References

  1. Hall, J. C. Adv. Genet. 48, 1–280 (2003).

    Article  CAS  Google Scholar 

  2. Stoleru, D., Peng, Y., Agosto, J. & Rosbash, M. Nature 431, 862–868 (2004).

    Article  ADS  CAS  Google Scholar 

  3. Grima, B., Chélot, E., Xia, R. & Rouyer, F. Nature 431, 869–873 (2004).

    Article  ADS  CAS  Google Scholar 

  4. Helfrich-Förster, C. Microsc. Res. Tech. 62, 94–102 (2003).

    Article  Google Scholar 

  5. Renn, S. C., Park, J. H., Rosbash, M., Hall, J. C. & Taghert, P. H. Cell 99, 791–802 (1999).

    Article  CAS  Google Scholar 

  6. Blanchardon, E. et al. Eur. J. Neurosci. 13, 871–888 (2001).

    Article  CAS  Google Scholar 

  7. Kaneko, M., Park, J. H., Cheng, Y., Hardin, P. E. & Hall, J. C. J. Neurobiol. 43, 207–233 (2000).

    Article  CAS  Google Scholar 

  8. Nitabach, M. N., Blau, J. & Holmes, T. C. Cell 109, 485–495 (2002).

    Article  CAS  Google Scholar 

  9. Peng, Y., Stoleru, D., Levine, J. D., Hall, J. C. & Rosbash, M. PLoS Biol. 1 E13 (2003).

    Article  Google Scholar 

  10. Lin, Y., Stormo, G. D. & Taghert, P. H. J. Neurosci. 24, 7951–7957 (2004).

    Article  CAS  Google Scholar 

  11. Yoshii, T. et al. J. Insect Physiol. 50, 479–488 (2004).

    Article  CAS  Google Scholar 

  12. Helfrich-Förster, C. J. Biol. Rhythms 15, 135–154 (2000).

    Article  Google Scholar 

  13. Pittendrigh, C. S. & Daan, S. J. Comp. Physiol. A 106, 333–355 (1976).

    Article  Google Scholar 

  14. Lee, H. S. et al. J. Biol. Rhythms 18, 435–449 (2003).

    Article  CAS  Google Scholar 

  15. Jagota, A. de la Iglesia, H. O. & Schwartz, W. J. Nature Neurosci. 3, 372–376 (2000).

    Article  CAS  Google Scholar 

  16. Veleri, S., Brandes, C., Helfrich-Förster, C., Hall, J. C. & Stanewsky, R. Curr. Biol. 13, 1758–1767 (2003).

    Article  CAS  Google Scholar 

  17. Myers, E. M., Yu, J., Sehgal, A., Curr. Biol. 13, 526–533 (2003).

    Article  CAS  Google Scholar 

  18. Tanoue, S., Krishnan, P., Krishnan, B., Dryer, S. E. & Hardin, P. E. Curr. Biol. 14, 638–649 (2004).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. the Department of Neurology, University of Massachusetts Medical School, Worcester, 01655, Massachusetts, USA

    William J. Schwartz

Authors
  1. William J. Schwartz
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Schwartz, W. Sunrise and sunset in fly brains. Nature 431, 751–752 (2004). https://doi.org/10.1038/431751a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/431751a

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing