An atomic picture of how anthrax toxin binds to its host's cells reveals that the toxin commandeers a host receptor protein and tricks it into helping the toxin enter the cell.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Jefferds, M. D. et al. Emerg. Infect. Dis. 8, 1138–1144 (2002).
Santelli, E., Bankston, L. A., Leppla, S. H. & Liddington, R. C. Nature 430, 905–908 (2004).
Wigelsworth, D. J. et al. J. Biol. Chem. 279, 23349–23356 (2004).
Lacy, D. B. et al. Proc. Natl Acad. Sci. USA 101, 6367–6372 (2004).
Emsley, J., Knight, C. G., Farndale, R. W., Barnes, M. J. & Liddington, R. C. Cell 101, 47–56 (2000).
Petosa, C., Collier, R. J., Klimpel, K. R., Leppla, S. H. & Liddington, R. C. Nature 385, 833–838 (1997).
Leppla, S. H. Proc. Natl Acad. Sci. USA 79, 3162–3166 (1982).
Park, J. M., Greten, F. R., Li, Z. W. & Karin, M. Science 297, 2048–2051 (2002).
Blaustein, R. O., Koehler, T. M., Collier, R. J. & Finkelstein, A. Proc. Natl Acad. Sci. USA 86, 2209–2213 (1989).
Bell, S. E. et al. J. Cell Sci. 114, 2755–2773 (2001).
Galdiero, S. & Gouaux, E. Protein Sci. 13, 1503–1511 (2004).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Bann, J., Hultgren, S. Anthrax hijacks host receptor. Nature 430, 843–844 (2004). https://doi.org/10.1038/430843a
Published:
Issue Date:
DOI: https://doi.org/10.1038/430843a
