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Biological chemistry

The making of Moco

Nature volume 430, pages 736737 (12 August 2004) | Download Citation


Nature exploits the unique chemistry of molybdenum in many reactions. Structures of the enzyme Cnx1 reveal unexpected mechanisms for slotting the metal ion into its reactive position in the cofactor Moco.

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Author information


  1. William N. Hunter is in the Division of Biological Chemistry and Molecular Microbiology, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK.

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