News & Views | Published:

Biological chemistry

The making of Moco

Nature volume 430, pages 736737 (12 August 2004) | Download Citation

Subjects

Nature exploits the unique chemistry of molybdenum in many reactions. Structures of the enzyme Cnx1 reveal unexpected mechanisms for slotting the metal ion into its reactive position in the cofactor Moco.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    in Molybdenum Cofactors and Model Systems (eds Stiefel, E. I., Coucouvanis, D. & Newton, N. W.) 1–19 (Am. Chem. Soc., Washington DC, 1993).

  2. 2.

    , & Annu. Rev. Biochem. 66, 233–267 (1997).

  3. 3.

    et al. Nature 430, 803–806 (2004).

  4. 4.

    & Curr. Opin. Struct. Biol. 12, 709–720 (2002).

  5. 5.

    et al. Nature 414, 325–329 (2001).

  6. 6.

    et al. J. Mol. Biol. 312, 405–418 (2001).

Download references

Author information

Affiliations

  1. William N. Hunter is in the Division of Biological Chemistry and Molecular Microbiology, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK. w.n.hunter@dundee.ac.uk

    • William N. Hunter

Authors

  1. Search for William N. Hunter in:

About this article

Publication history

Published

DOI

https://doi.org/10.1038/430736a

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing