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Cell biology

Barbed ends rule

To explore their surroundings, cells use probes of various shapes. Whether the probes are broad and flat, or long and thin, seems to be regulated by proteins at the growing ends of actin filaments.

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Figure 1: Model for how the growing ends of actin filaments regulate cellular protrusions.

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Schafer, D. Barbed ends rule. Nature 430, 734–735 (2004). https://doi.org/10.1038/430734a

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