Biotechnology

Surrogate broodstock produces salmonids

Trout offspring can be created from trout-donor germ cells transplanted into salmon.

Abstract

A worldwide decline in the number of wild salmonids1 calls for strategies to restore endangered populations. Here we show that germ cells can be transplanted between two different salmonid species, with the subsequent production of xenogenic, donor-derived offspring. This pioneering xenotransplantation technology may eventually find applications in facilitating the production of commercially valuable fish, as well as in species conservation.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

Figure 1: Colonization, proliferation and germline transmission of donor-derived trout germ cells transplanted into salmon embryos.
Figure 2

References

  1. 1

    Bella, D. A. Science 295, 1236 (2002).

    CAS  Article  Google Scholar 

  2. 2

    Wylie, C. Cell 96, 165–174 (1999).

    CAS  Article  Google Scholar 

  3. 3

    Lawrence, P. A., Ashburner, M. & Johnston, P. Genetics 134, 1145–1148 (1993).

    CAS  PubMed  PubMed Central  Google Scholar 

  4. 4

    Ono, T., Yokoi, R. & Aoyama, H. Exp. Anim. 45, 347–352 (1996).

    CAS  Article  Google Scholar 

  5. 5

    Takeuchi, Y., Yoshizaki, G., Kobayashi, T. & Takeuchi, T. Biol. Reprod. 67, 1087–1097 (2002).

    CAS  Article  Google Scholar 

  6. 6

    Takeuchi, Y., Yoshizaki, G. & Takeuchi, T. Biol. Reprod. 69, 1142–1149 (2003).

    CAS  Article  Google Scholar 

  7. 7

    McKay, S. J., Devlin, R. H. & Smith, M. J. Can. J. Fish. Aquat. Sci. 53, 1165–1176 (1996).

    CAS  Article  Google Scholar 

  8. 8

    Kobayashi, T., Takeuchi, Y., Yoshizaki, G. & Takeuchi, T. Fish Physiol. Biochem. 23, 479–480 (2003).

    Article  Google Scholar 

Download references

Author information

Affiliations

Authors

Corresponding author

Correspondence to Goro Yoshizaki.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Supplementary information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Takeuchi, Y., Yoshizaki, G. & Takeuchi, T. Surrogate broodstock produces salmonids. Nature 430, 629–630 (2004). https://doi.org/10.1038/430629a

Download citation

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing