Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Brief Communication
  • Published:

Biotechnology

Surrogate broodstock produces salmonids

Trout offspring can be created from trout-donor germ cells transplanted into salmon.

Abstract

A worldwide decline in the number of wild salmonids1 calls for strategies to restore endangered populations. Here we show that germ cells can be transplanted between two different salmonid species, with the subsequent production of xenogenic, donor-derived offspring. This pioneering xenotransplantation technology may eventually find applications in facilitating the production of commercially valuable fish, as well as in species conservation.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Colonization, proliferation and germline transmission of donor-derived trout germ cells transplanted into salmon embryos.
Figure 2

Similar content being viewed by others

References

  1. Bella, D. A. Science 295, 1236 (2002).

    Article  CAS  Google Scholar 

  2. Wylie, C. Cell 96, 165–174 (1999).

    Article  CAS  Google Scholar 

  3. Lawrence, P. A., Ashburner, M. & Johnston, P. Genetics 134, 1145–1148 (1993).

    CAS  PubMed  PubMed Central  Google Scholar 

  4. Ono, T., Yokoi, R. & Aoyama, H. Exp. Anim. 45, 347–352 (1996).

    Article  CAS  Google Scholar 

  5. Takeuchi, Y., Yoshizaki, G., Kobayashi, T. & Takeuchi, T. Biol. Reprod. 67, 1087–1097 (2002).

    Article  CAS  Google Scholar 

  6. Takeuchi, Y., Yoshizaki, G. & Takeuchi, T. Biol. Reprod. 69, 1142–1149 (2003).

    Article  CAS  Google Scholar 

  7. McKay, S. J., Devlin, R. H. & Smith, M. J. Can. J. Fish. Aquat. Sci. 53, 1165–1176 (1996).

    Article  CAS  Google Scholar 

  8. Kobayashi, T., Takeuchi, Y., Yoshizaki, G. & Takeuchi, T. Fish Physiol. Biochem. 23, 479–480 (2003).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Goro Yoshizaki.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Supplementary information

Rights and permissions

Reprints and permissions

About this article

Cite this article

Takeuchi, Y., Yoshizaki, G. & Takeuchi, T. Surrogate broodstock produces salmonids. Nature 430, 629–630 (2004). https://doi.org/10.1038/430629a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/430629a

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing