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Neurobiology

Odorant receptors make scents

The goal of making sense of the sense of smell has come a step closer. Work on fruitflies reveals that odorant receptors act as bidirectional chemical detectors and determine the function of sensory neurons.

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Figure 1: Linking odorant receptors to neuronal responses.

References

  1. Buck, L. & Axel, R. Cell 65, 175–187 (1991).

    Article  CAS  Google Scholar 

  2. Hallem, E. A., Ho, M. G. & Carlson, J. R. Cell 117, 965–979 (2004).

    Article  CAS  Google Scholar 

  3. Krautwurst, D., Yau, K. W. & Reed, R. R. Cell 95, 917–926 (1998).

    Article  CAS  Google Scholar 

  4. Zhao, H. et al. Science 279, 237–242 (1998).

    Article  ADS  CAS  Google Scholar 

  5. Dobritsa, A. A., van der Goes van Naters, W., Warr, C. G., Steinbrecht, R. A. & Carlson, J. R. Neuron 37, 827–841 (2003).

    Article  CAS  Google Scholar 

  6. Malnic, B., Hirono, J., Sato, T. & Buck, L. B. Cell 96, 713–723 (1999).

    Article  CAS  Google Scholar 

  7. Vosshall, L. B., Wong, A. M. & Axel, R. Cell 102, 147–159 (2000).

    Article  CAS  Google Scholar 

  8. Adrian, E. D. Acta Physiol. Scand. 29, 5–14 (1953).

    Article  CAS  Google Scholar 

  9. Friedrich, R. W. & Stopfer, M. Curr. Opin. Neurobiol. 11, 468–474 (2001).

    Article  CAS  Google Scholar 

Download references

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Friedrich, R. Odorant receptors make scents. Nature 430, 511–512 (2004). https://doi.org/10.1038/430511a

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