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Gene regulation

A reason for reading nonsense

Nature volume 429, pages 510–511 (2004)Cite this article

The process of transcribing DNA can itself regulate gene expression in yeast: in the case concerned it is the very act of reading the DNA, not the message produced, that carries out the regulatory job.

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Figure 1: Intergenic transcription and gene regulation.

References

  1. Martens, J. A., Laprade, L. & Winston, F. Nature 429, 571–574 (2004).

    Article  ADS  CAS  Google Scholar 

  2. Greger, I. H., Aranda, A. & Proudfoot, N. Proc. Natl Acad. Sci. USA 97, 8415–8420 (2000).

    Article  ADS  CAS  Google Scholar 

  3. Corbin, V. & Maniatis, T. Nature 337, 279–282 (1989).

    Article  ADS  CAS  Google Scholar 

  4. Meller, V. H. et al. Curr. Biol. 10, 136–143 (2000).

    Article  CAS  Google Scholar 

  5. Wutz, A., Rasmussen, T. P. & Jaenisch, R. Nature Genet. 30, 167–174 (2002).

    Article  CAS  Google Scholar 

  6. Sleutels, F., Tjon, G., Ludwig, T. & Barlow, D. P. EMBO J. 22, 3696–3704 (2003).

    Article  CAS  Google Scholar 

  7. Gribnau, J., Diderich, K., Pruzina, S., Calzolari, R. & Fraser, P. Mol. Cell 5, 377–386 (2000).

    Article  CAS  Google Scholar 

  8. Martens, J. A. & Winston, F. Genes Dev. 16, 2231–2236 (2002).

    Article  CAS  Google Scholar 

  9. Valerius, O., Brendel, C., Düvel, K. & Braus, G. H. J. Biol. Chem. 277, 21440–21445 (2002).

    Article  CAS  Google Scholar 

  10. Cawley, S. et al. Cell 116, 499–509 (2004).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Centre for Molecular Biology (ZMBH), University of Heidelberg, Im Neuenheimer Feld 282, Heidelberg, 69120, Germany

    Sabine Schmitt & Renato Paro

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  1. Sabine Schmitt
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  2. Renato Paro
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Schmitt, S., Paro, R. A reason for reading nonsense. Nature 429, 510–511 (2004). https://doi.org/10.1038/429510a

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