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Origins of licensing control

Organ development requires precise regulation of both the total number and the different types of cells. Much is known about how each process is controlled, but new light has been shed on how the two are linked.

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Figure 1: Regulation of cell proliferation and differentiation by Six and Hox proteins.


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Li, X., Rosenfeld, M. Origins of licensing control. Nature 427, 687–688 (2004).

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