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Guarding the guardian?

The diversity of cellular stresses that activate the 'guardian of the genome' — p53 — begs the question of how these signals all converge on one protein. Perhaps the key to this integration is the nucleolus.

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Correspondence to Karen H. Vousden.

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Horn, H., Vousden, K. Guarding the guardian?. Nature 427, 110–111 (2004).

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