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Cell biology

Shape-shifting protein channel

Newly made proteins are moved across cellular membranes through a protein channel. The crystal structure of this channel is now revealed and confirms expectations that it must change shape to allow proteins to pass.

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Figure 1: The SecYEβ channel13, with some of its binding partners and model substrates shown at the same scale.

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Correspondence to John F. Hunt.

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Benach, J., Hunt, J. Shape-shifting protein channel. Nature 427, 24–25 (2004). https://doi.org/10.1038/427024a

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