Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Neurobiology

Signals that make waves

Neurons in the brain release proteins called neurotrophins, which bind to glial cells and unleash a wave of calcium ions inside them. This could be the missing link in a communication circuit between glia and neurons.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

Figure 1: A multifunctional receptor.

References

  1. Rose, C. R. et al. Nature 426, 74–78 (2003).

    Article  ADS  CAS  Google Scholar 

  2. Huang, E. J. & Reichardt, L. F. Annu. Rev. Neurosci. 24, 677–736 (2001).

    Article  CAS  Google Scholar 

  3. Chao, M. V. Nature Rev. Neurosci. 4, 299–309 (2003).

    Article  CAS  Google Scholar 

  4. Blum, R., Kafitz, K. W. & Konnerth, A. Nature 419, 687–693 (2002).

    Article  ADS  CAS  Google Scholar 

  5. Allendoerfer, K. L. et al. J. Neurosci. 14, 1795–1811 (1994).

    Article  CAS  Google Scholar 

  6. Biffo, S., Offenhauser, N., Carter, B. D. & Barde, Y. A. Development 121, 2461–2470 (1995).

    CAS  Google Scholar 

  7. Alderson, R. F., Curtis, R., Alterman, A. L., Lindsay, R. M. & DiStefano, P. S. Brain Res. 871, 210–222 (2000).

    Article  CAS  Google Scholar 

  8. Hapner, S. J., Boeshore, K. L., Large, T. H. & Lefcort, F. Dev. Biol. 201, 90–100 (1998).

    Article  CAS  Google Scholar 

  9. Yacoubian, T. A. & Lo, D. C. Nature Neurosci. 3, 342–349 (2000).

    Article  CAS  Google Scholar 

  10. Baxter, G. T. et al. J. Neurosci. 17, 2683–2690 (1997).

    Article  CAS  Google Scholar 

  11. Haydon, P. G. Nature Rev. Neurosci. 2, 185–193 (2001).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Reichardt, L. Signals that make waves. Nature 426, 25–26 (2003). https://doi.org/10.1038/426025a

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/426025a

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing