Mutations in model organisms are grist to the geneticists' mill: they help in assigning function to genes. Chromosome engineering in mice makes it easier to pinpoint the location of randomly induced mutations.
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Rossant, J. A balancing act. Nature 425, 29–31 (2003). https://doi.org/10.1038/425029a
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DOI: https://doi.org/10.1038/425029a
