Cells are packed with large molecules. The ramifications of this 'crowding' for a wide range of intracellular processes are only now becoming more generally understood.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Probing the structure of water in individual living cells
Nature Communications Open Access 20 June 2024
-
Macromolecular crowding regulates matrix composition and gene expression in human gingival fibroblast cultures
Scientific Reports Open Access 04 February 2023
-
Quantitative evaluation of macromolecular crowding environment based on translational and rotational diffusion using polarization dependent fluorescence correlation spectroscopy
Scientific Reports Open Access 19 May 2021
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Notes
*EMBO Workshop: Biological Implications of Macromolecular Crowding. Palacio de Magalia, Spain, 14–18 June 2003 (http://www.cib.csic.es/~revers/embo2003).
References
Ellis, R. J. Trends Biochem. Sci. 26, 597–604 (2001).
Hall, D. & Minton, A. P. Biochim. Biophys. Acta 1649, 127–139 (2003).
Medalia, O. et al. Science 298, 1209–1213 (2002).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ellis, R., Minton, A. Join the crowd. Nature 425, 27–28 (2003). https://doi.org/10.1038/425027a
Issue Date:
DOI: https://doi.org/10.1038/425027a
This article is cited by
-
Probing the structure of water in individual living cells
Nature Communications (2024)
-
Structural and functional complexity of HSP90 in cellular homeostasis and disease
Nature Reviews Molecular Cell Biology (2023)
-
Macromolecular crowding regulates matrix composition and gene expression in human gingival fibroblast cultures
Scientific Reports (2023)
-
Improving coarse-grained models of protein folding through weighting of polar-polar/hydrophobic-hydrophobic interactions into crowded spaces
Journal of Molecular Modeling (2022)
-
Quantitative evaluation of macromolecular crowding environment based on translational and rotational diffusion using polarization dependent fluorescence correlation spectroscopy
Scientific Reports (2021)