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Cancer

Protective packaging for DNA

Histone proteins are best known for their structural role in packaging DNA into a compact form. But it seems that one such protein also works as a tumour suppressor, helping to prevent cancer developing.

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Figure 1: Model of the response to DNA double-strand breaks in mammalian cells, incorporating the new results1,2.

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Downs, J., Jackson, S. Protective packaging for DNA. Nature 424, 732–734 (2003). https://doi.org/10.1038/424732a

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