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Signal transduction

Life on Mars, cellularly speaking

A key molecular switch, known as the Ha-Ras protein, is active not only at a cell's outer membrane but also on intracellular membranes. This surprising discovery hints at unsuspected complexity in cellular signalling.

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Figure 1: Switching on Ras in different cellular locations.

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Di Fiore, P. Life on Mars, cellularly speaking. Nature 424, 624–625 (2003). https://doi.org/10.1038/424624a

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