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Telomeres

Taking the measure

Nature volume 423, pages 926–927 (2003)Cite this article

Telomeres — the tips of chromosomes — need to be preserved, and this involves replenishing telomeric DNA when it has been eroded. But telomeres must not become too long, and one aspect of length control is now revealed.

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Figure 1: Model for telomere length control.

References

  1. Loayza, D. & de Lange, T. Nature 423, 1013–1018 (2003).

    Article  CAS  ADS  Google Scholar 

  2. Colgin, L. M., Baran, K., Baumann, P., Cech, T. R. & Reddel, R. R. Curr. Biol. 13, 942–946 (2003).

    Article  CAS  Google Scholar 

  3. Lee, H.-W. et al. Nature 392, 569–574 (1998).

    Article  CAS  ADS  Google Scholar 

  4. Damm, K. et al. EMBO J. 20, 6958–6968 (2001).

    Article  CAS  Google Scholar 

  5. Evans, S. K. & Lundblad, V. Science 286, 117–120 (1999).

    Article  CAS  Google Scholar 

  6. Marcand, S., Gilson, E. & Shore, D. Science 275, 986–990 (1997).

    Article  CAS  Google Scholar 

  7. Smogorzewska, A. et al. Mol. Cell. Biol. 20, 1659–1668 (2000).

    Article  CAS  Google Scholar 

  8. Baumann, P. & Cech, T. R. Science 297, 1171–1175 (2001).

    Article  ADS  Google Scholar 

  9. Mitton-Fry, R. M., Anderson, E. M., Hughes, T. R., Lundblad, V. & Wuttke, D. S. Science 296, 145–147 (2002).

    Article  CAS  ADS  Google Scholar 

  10. Peersen, O. B., Ruggles, J. A. & Schultz, S. C. Nature Struct. Biol. 9, 182–187 (2002).

    CAS  PubMed  Google Scholar 

  11. Chandra, A., Hughes, T. R., Nugent, C. I. & Lundblad, V. Genes Dev. 15, 404–414 (2001).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, 77030, Texas, USA

    Vicki Lundblad

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  1. Vicki Lundblad
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Correspondence to Vicki Lundblad.

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Lundblad, V. Taking the measure. Nature 423, 926–927 (2003). https://doi.org/10.1038/423926a

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