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Cancer

Out of air is not out of action

Nature volume 423, pages 593–595 (2003)Cite this article

Starving cancers of oxygen would seem to be a good way of killing them, but the presence of oxygen-deprived areas in tumours appears to correlate with poor prognosis. A molecular explanation for this has now been found.

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Figure 1: Short of oxygen.
Figure 2: How tumours cope with — and can benefit from — a lack of oxygen.

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Author information

Authors and Affiliations

  1. the Urologic Oncology Branch,

    Donald P. Bottaro

  2. the Invasion and Metastasis Section, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, 20892-1500, Maryland, USA

    Lance A. Liotta

Authors
  1. Donald P. Bottaro
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  2. Lance A. Liotta
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Corresponding author

Correspondence to Lance A. Liotta.

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Bottaro, D., Liotta, L. Out of air is not out of action. Nature 423, 593–595 (2003). https://doi.org/10.1038/423593a

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