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Stem cells

Self-renewal writ in blood

The ability to self-renew is a defining property of stem cells, and a protein in blood stem cells that controls their self-renewal has been discovered. That same protein is also crucial for the development of leukaemia.

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Figure 1: The choices available to haematopoietic stem cells (HSCs) upon division.


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Correspondence to John E. Dick.

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Dick, J. Self-renewal writ in blood. Nature 423, 231–232 (2003).

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