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Structural biology

Life's transistors

Voltage-gated ion channels control electrical activity in nerve, muscle and many other cell types. The crystal structure of a bacterial voltage-gated channel reveals the astonishingly simple design of its voltage sensor.

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Figure 1: Voltage sensing in a potassium ion channel.


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Correspondence to Fred J. Sigworth.

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Sigworth, F. Life's transistors. Nature 423, 21–22 (2003).

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