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Stem cells

Fusion brings down barriers

It remains uncertain how tissue-specific stem cells could generate the mature cell types of another tissue. In one instance, where bone-marrow-derived stem cells repair damaged liver in mice, cell fusion is the answer.

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Figure 1: Possible mechanisms by which transplanted blood cells could transform into liver cells.
Figure 2: Formation and reduction of hybrids.


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Correspondence to Alexander Medvinsky or Austin Smith.

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Medvinsky, A., Smith, A. Fusion brings down barriers. Nature 422, 823–825 (2003).

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