Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Developmental biology

A hairy situation

A key step in hair-follicle development is the rearrangement of epithelial stem cells. It seems that reduced production of an adhesion protein, through the concerted action of two signalling pathways, is crucial for this process.

Your institute does not have access to this article

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

Figure 1: Making a bud.

References

  1. Jamora, C., DasGupta, R., Kocieniewski, P. & Fuchs, E. Nature 422, 317–322 (2003).

    ADS  CAS  Article  Google Scholar 

  2. Fuchs, E. & Raghavan, S. Nature Rev. Genet. 3, 199–209 (2002).

    CAS  Article  Google Scholar 

  3. Eastman, Q. & Grosschedl, R. Curr. Opin. Cell Biol. 11, 233–240 (1999).

    CAS  Article  Google Scholar 

  4. Huelsken, J. et al. Cell 105, 533–545 (2001).

    CAS  Article  Google Scholar 

  5. Botchkarev, V. A. et al. Nature Cell Biol. 1, 158–164 (1999).

    CAS  Article  Google Scholar 

  6. Takeichi, M. Science 251, 1451–1455 (1991).

    ADS  CAS  Article  Google Scholar 

  7. Hirai, Y. et al. Development 105, 271–277 (1989).

    CAS  PubMed  Google Scholar 

  8. Vasioukhin, V. et al. Cell 104, 605–617 (2001).

    CAS  Article  Google Scholar 

  9. Gumbiner, B. M. J. Cell Biol. 148, 399–403 (2000).

    CAS  Article  Google Scholar 

  10. Perez-Moreno, M., Jamora, C. & Fuchs, E. Cell 112, 535–548 (2003).

    CAS  Article  Google Scholar 

  11. Cano, A. et al. Nature Cell Biol. 2, 76–83 (2000).

    ADS  CAS  Article  Google Scholar 

  12. Batle, E. et al. Nature Cell Biol. 2, 84–89 (2000).

    ADS  Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Yann Barrandon.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Barrandon, Y. A hairy situation. Nature 422, 272–273 (2003). https://doi.org/10.1038/422272a

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/422272a

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing