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Developmental biology

A twist in a mouse tale

Studies of the retinoblastoma gene can still deliver surprises, and enlightenment. Several of the abnormalities in mice lacking this gene are, it seems, the indirect consequence of a placental defect.

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References

  1. Wu, L. et al. Nature 421, 942–947 (2003).

    ADS  CAS  Article  Google Scholar 

  2. Lee, E. Y.-H. P. et al. Nature 359, 288–294 (1992).

    ADS  CAS  Article  Google Scholar 

  3. Jacks, T. et al. Nature 359, 295–300 (1992).

    ADS  CAS  Article  Google Scholar 

  4. Clarke, A. R. et al. Nature 359, 328–330 (1992).

    ADS  CAS  Article  Google Scholar 

  5. Rossant, J. & Cross, J. C. Nature Rev. Genet. 2, 538–548 (2001).

    CAS  Article  Google Scholar 

  6. Williams, B. O. et al. EMBO J. 13, 4251–4259 (1994).

    CAS  Article  Google Scholar 

  7. Maandag, E. C. et al. EMBO J. 13, 4260–4268 (1994).

    CAS  Article  Google Scholar 

  8. Tsai, K. Y. et al. Mol. Cell 2, 293–304 (1998).

    CAS  Article  Google Scholar 

  9. Ziebold, U., Reza, T., Caron, A. & Lees, J. A. Genes Dev. 15, 386–391 (2001).

    CAS  Article  Google Scholar 

  10. Lasorella, A., Noseda, M., Beyna, M., Yokota, Y. & Iavarone, A. Nature 407, 592–598 (2000).

    ADS  CAS  Article  Google Scholar 

Download references

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Correspondence to Nick Dyson.

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Dyson, N. A twist in a mouse tale. Nature 421, 903–904 (2003). https://doi.org/10.1038/421903a

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